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Not quite what the XKCD is talking about, but my favorite linguistic phenomenon: https://en.wikipedia.org/wiki/Dysphemism
I prefer cacophemism. You can make some really fucked up new concepts by replacing eu- (good/well) with caco- (bad):
cacology, cacogenics, cacophoria (I guess dysphoria got there first), cacoangelium and my favourite, cacothanasia.
